216 reviews
Updated April 2026 · about a 6 minute read
No clinic chair required, just a serum and a gentle at home rhythm.
The short answer
Mesotherapy is a clinical procedure where a trained practitioner injects a tailored blend of ingredients into the skin, so it belongs in a clinic, not at home. The gentle cosmetic alternative most people reach for is a PDRN serum applied on the surface of the skin, on its own or with an at home skin tool. Browse the CureNex range.
If you have ever heard the word mesotherapy and wondered whether it is something you could try yourself, this is the honest version. There is a clinical treatment done by professionals, and there is a much gentler at home cosmetic approach that gives you the ritual without the injecting. Here is the full picture.
What is mesotherapy?
Mesotherapy is a cosmetic procedure in which a qualified practitioner delivers a tailored solution into the skin using very fine injections. Because it works beneath the surface, it is a clinical treatment carried out in a clinic by trained professionals. It is not a do it yourself activity, and we do not sell injectables. If it appeals to you, the right first step is a consultation with a practitioner who can talk through suitability and risks.
The at home alternative
If injecting is not for you (and for most people at home, it really should not be), the popular cosmetic alternative is a PDRN serum you apply on the surface of the skin, paired with a gentle at home skin tool (a roller, stamp or pen). The at home skin tool creates tiny surface channels so the serum can settle in where you want it, with no injecting involved. This is the approach we focus on. For the safe method, see our guide to the treatment at home.
Same ritual, none of the injecting: a good serum and a gentle at home skin tool.
Where CureNex fits in
CureNex is a professional grade PDRN (salmon DNA) range you apply to the surface of your skin, formulated with ingredients like hyaluronic acid and peptides. It is a lovely companion for an at home routine, valued for supporting the look of hydrated, calm, even skin over time.
What people love about a CureNex and at home skin tool routine (cosmetically)
- Better absorption: the tiny surface channels from a gentle at home skin tool help the serum sink in.
- Hydration: hyaluronic acid in the formula supports a plump, dewy look.
- Comfort: soothing ingredients help calm the look of redness after your routine.
- Flexible: easy to tailor to your routine and skin goals.
- Consistent: a sustainable at home rhythm that supports the look of even, radiant skin over time.
CureNex Salmon DNA PDRN Skin Booster with Peptides
A cushioning PDRN and peptide booster for the look of hydrated, calm skin, lovely on its own or with your at home skin tool.
$79 AUDAfterpay available · free shipping over $150Shop the skin booster →
Final thoughts
Mesotherapy is a clinical procedure best left to qualified practitioners. For a gentle at home cosmetic approach, a CureNex PDRN serum applied on the surface of the skin with a shallow at home skin tool (0.25 to 0.5mm) is a beautiful way to support the look of your skin without any injecting. Browse our salmon DNA serums and skin boosters and our at home skin tools to get started.
Frequently asked questions
Is mesotherapy something I can do at home?
No, mesotherapy involves injecting beneath the skin and should only be performed by a qualified practitioner in a clinic. For home use, a PDRN serum applied with a gentle at home skin tool (a roller, stamp or pen) is the cosmetic alternative.
What is the difference between mesotherapy and a needling treatment?
Mesotherapy injects a solution into the skin, which is a clinical treatment. A needling treatment creates tiny surface channels that help a serum absorb, and a gentle version can be done at home with a cosmetic serum and an at home skin tool.
Can I use CureNex without injections?
Yes. CureNex is a cosmetic serum you apply to the surface of your skin, on its own or with a gentle at home skin tool (a roller, stamp or pen). No injecting required.
Disclaimer: these are cosmetics, not therapeutic goods, and are not intended to diagnose, treat, cure or prevent any disease or condition. Mesotherapy is a clinical procedure performed by qualified practitioners and is described here for information only. An at home skin tool routine should be gentle (0.25 to 0.5mm). Always patch test; not suitable for those with fish allergies.
