216 reviews
Updated April 2026 · about a 6 minute read

Salmon DNA you can use at home, no clinic appointment needed.
The short answer
Rejuran is a range of clinic injectable skin boosters (PN and PDRN from salmon DNA) given by qualified practitioners, so it is a therapeutic good and not something we sell. If you would rather stay at home, salmon DNA (PDRN) serums you apply yourself give you a gentle, cosmetic way to enjoy the same hero ingredient. Browse PDRN serums.
If you have been reading about Rejuran skin boosters and wondering whether there is a gentler way to enjoy salmon DNA without booking a clinic appointment, this guide is for you. Below is how the Rejuran range breaks down, and a cosmetic salmon DNA serum you can use at home for each one.
What is Rejuran?
Rejuran is a well known range of injectable skin boosters containing polynucleotides (PN) and polydeoxyribonucleotide (PDRN), both derived from salmon DNA (around 95% similar to human DNA). Because they are injected, they are clinical treatments performed by qualified practitioners and regulated as therapeutic goods, not something to do at home. We do not sell injectables.
The good news for anyone who would rather stay at home: you can enjoy salmon DNA cosmetically with PDRN serums you smooth onto the surface of the skin. That is the approach our products are made for.
A note on using salmon DNA at home
Salmon DNA ampoules are made to be applied to the skin and worked in with a gentle at home skin tool routine (0.25 to 0.5mm), never injected. Used consistently, they support the look of hydrated, even, radiant skin.
The Rejuran range, and an at home alternative for each
Rejuran I (eye area)
An injectable aimed at the look of the eye area (1ml syringe).
At home alternative: CureNex Eye PN, a PN serum with HA that you apply yourself, in a larger 2ml size, to support the look of the delicate eye area.
Rejuran S
An injectable focused on the look of scarring and uneven tone (2% PN, 1ml syringe).
At home alternative: our Rejuva Healer S (NAD+, PDRN & HA) serum, made to support the look of even, hydrated, fresh skin.
Rejuran HB
An injectable with added HA aimed at hydration and skin comfort (1ml syringe).
At home alternative: HP Cell VITARAN, a salmon DNA ampoule with HA plus a broad blend of vitamins and amino acids (54 supporting ingredients versus Rejuran's six).
Rejuran Healer Trueskin Essence
An injectable for the whole face combining PN with hydration (2% PN, 2 x 2ml syringes).
At home alternative: a daily PDRN serum from our PDRN range, used morning and night.

The hero ingredient is the same salmon DNA. The difference is a clinic chair versus your own bathroom bench.
Want a more advanced formula?
If you like the idea of exosomes, which act as delivery vesicles helping carry salmon DNA into the skin, consider the Vitaran range.
How salmon DNA serums compare
Many salmon DNA serums pair PDRN with a broader mix of supporting ingredients: hyaluronic acid, peptides, antioxidants, exosomes and botanicals, so they can support several aspects of how your skin looks at once (hydration, the appearance of tone and texture). It is not that one is better than another; it is about matching the formula and format to how you like to use your skincare.
Choosing the right option for you
- Understand your goal. Hydration, the look of even tone, comfort for sensitive skin? Different formulas lean different ways.
- Pick your format. Prefer a clinical injectable? See a qualified practitioner. Prefer to stay at home? Choose a PDRN serum you apply yourself with a gentle at home skin tool.
- Be consistent. Results from any cosmetic routine build with time, regular use plus a good routine makes the difference.
- Choose quality. Professional grade, well formulated products from a trusted source give you the best experience.
Ready to start? Browse salmon DNA serums and skin boosters.

CureNex Salmon DNA & Peptide Daily Serum
A gentle daily salmon DNA serum you can use on its own or with your at home skin tool.
$49.50 AUDAfterpay available · free shipping over $150Shop the daily serum →
Frequently asked questions
Is Rejuran an injectable?
Yes, Rejuran is a range of injectable skin boosters administered by qualified practitioners in a clinic. We do not sell injectables; we stock salmon DNA serums you apply yourself at home.
Can I use salmon DNA at home instead of Rejuran?
Yes, PDRN serums you apply with a gentle at home routine (0.25 to 0.5mm) are the popular at home, cosmetic way to enjoy salmon DNA, without injecting.
What is a good at home alternative to Rejuran?
Depending on your goal: CureNex Eye PN for the eye area, HP Cell VITARAN for a vitamin rich ampoule, Rejuva Healer S for a NAD+, PDRN and HA serum, or Vitaran for an exosome and PDRN formula.
Disclaimer: these are cosmetics, not therapeutic goods, and are not intended to diagnose, treat, cure or prevent any disease or condition. Rejuran is an injectable given by qualified practitioners and is described here for comparison only. An at home routine should be gentle (0.25 to 0.5mm); our products are not for injection. Always patch test; not suitable for those with fish allergies.


