Rejuran Skin Boosters: Differences & Benefits (and Topical Options)
Short answer: Rejuran skin boosters are clinic injectables containing polynucleotides (PN/PDRN) from salmon DNA, given by a practitioner. The variants (Healer, I, S) target different things. If you'd prefer an at-home option, there are topical salmon DNA serums you apply with a gentle treatment. Here's the rundown. Browse topical salmon DNA serums.
What is a Rejuran skin booster?
Rejuran is a popular injectable treatment built around polynucleotides (PN) and PDRN derived from salmon DNA. Because it's injected, it's a clinical procedure performed by qualified practitioners and regulated as a therapeutic good. It's favoured for its gentle approach, but it's not a DIY product, and we don't sell injectables.
The Rejuran variants
Rejuran Healer
The best-known variant, focused on overall skin quality. It contains polynucleotides and is used cosmetically to support the look of fresh, even, comfortable skin.
Rejuran I
A more concentrated polynucleotide formulation used for the look of more significant skin concerns, it requires a professional consultation to plan.
Rejuran S
Aimed at the look of texture, pore appearance and radiance, often used as part of a broader skin routine.
The topical, at-home alternative
You don't need injections to enjoy salmon DNA. Topical PDRN serums applied with a gentle at-home treatment (0.25-0.5mm) let you build a sustainable routine that supports the look of hydrated, even, radiant skin. Browse the PDRN serum range.
Why people like topical salmon DNA serums
- Broader ingredient blends: many pair PDRN with hyaluronic acid, peptides, antioxidants and exosomes to support several aspects of how skin looks at once.
- Hydration: HA in the formula supports a plump, dewy look.
- Comfort: gentle, soothing formulas that suit sensitive-feeling skin.
- Convenience: no appointment, no downtime, easy to use consistently at home.
It's not that topical is "better" than injectable or vice versa, they're different routes. It's about choosing the format that fits how you like to care for your skin.
Choosing the right option for you
- Know your goal: hydration, the look of even tone, comfort for sensitive skin?
- Pick your route: a clinical injectable (see a qualified practitioner) or an at-home topical PDRN serum with a gentle treatment.
- Set realistic expectations: cosmetic results build with consistency. A common at-home rhythm is three to five gentle treatment sessions spaced about four weeks apart, with daily topical use in between.
- Choose quality: well-formulated, professional-grade products from a trusted source.
Final thoughts
Rejuran is a trusted injectable option for those who want a clinic treatment. For an at-home, cosmetic approach, topical salmon DNA serums with a gentle treatment are a lovely way to support the look of healthy, radiant skin. Whichever route you choose, consistency and quality matter most.
Shop topical salmon DNA skin boosters →
Frequently asked questions
What is a Rejuran skin booster made of?
Rejuran skin boosters are injectables built around polynucleotides (PN) and PDRN derived from salmon DNA, administered by a qualified practitioner.
What's the difference between Rejuran Healer, I and S?
Broadly: Healer focuses on overall skin quality, I is a more concentrated formulation for the look of more significant concerns, and S targets the look of texture, pores and radiance. A practitioner can advise on suitability.
Is there an at-home alternative to Rejuran?
Yes, topical salmon DNA (PDRN) serums applied with a gentle treatment (0.25-0.5mm) are the popular cosmetic, at-home alternative. No injecting required.
Disclaimer: The products we sell are topical cosmetics, not therapeutic goods, and are not intended to diagnose, treat, cure or prevent any disease or condition. Rejuran is an injectable administered by qualified practitioners and is described here for comparison only. An at-home treatment should be gentle (0.25-0.5mm), our products are not for injection. Always patch test; not suitable for those with fish allergies.
Rejuran by product form: skin booster, ampoule, cream and mask (and the at home Vitaran alternative)
People often search for Rejuran by the format they have in mind, whether that is a "skin booster", "turnover ampoule", "cream" or "mask". Here is what each term usually refers to, and the topical salmon DNA option many Australians choose instead: the Vitaran range, built around CS PDRN (salmon DNA), exosomes and NMN.
Rejuran skin booster and "turnover ampoule"
"Skin booster" and "ampoule" usually describe the single dose vials used in clinic injectable protocols. For an at home, topical route, the HP Cell Vitaran Skin Booster is a popular cosmetic alternative. It is a topical booster with one of the richest ingredient profiles available, pairing CS PDRN salmon DNA with 54 active ingredients (12 vitamins, 7 minerals, 24 amino acids, 4 coenzymes, glutathione, proteoglycan and hyaluronic acid). Applied with a gentle treatment at 0.25 to 0.5mm, it supports the look of hydrated, even and radiant skin, with no injecting.
Rejuran cream
If you would like a leave on step, the Vitaran PDRN and Exosome Capsule Cream uses capsule technology to help keep its actives fresh, supporting the appearance of plump, comfortable skin with an even tone as part of a daily routine.
Rejuran mask and sheet step
For a treat step, layer a topical salmon DNA serum from the Vitaran range under your usual mask or moisturiser to support a hydrated, dewy look.
Why people choose Vitaran as their at home option
- Richer ingredient blend: CS PDRN salmon DNA plus exosomes, NMN, niacinamide and more, designed to support several aspects of how skin looks at once.
- Capsule freshness: dual chamber and capsule technology helps keep actives at full strength until you use them.
- No appointment: a sustainable rhythm at home, with gentle treatment sessions spaced about four weeks apart and daily topical use in between.
It is not that topical is "better" than injectable. They are simply different routes, and many Australians prefer a cosmetic option they can use at home and stay consistent with.
Shop the Vitaran salmon DNA range
More Rejuran questions
What is the Rejuran Turnover Ampoule?
It is a term people use for the single dose vials in clinic injectable treatments. For an at home, topical route, a salmon DNA skin booster such as the HP Cell Vitaran Skin Booster is a popular cosmetic alternative, applied to the skin rather than injected.
Is there a Rejuran cream or mask I can use at home?
There is no at home version of the injectable, but topical salmon DNA creams such as the Vitaran Capsule Cream, and layering a Vitaran PDRN serum under a mask step, are the popular cosmetic options.
How does the HP Cell Vitaran Skin Booster compare to a Rejuran skin booster?
Rejuran is a clinic injectable. The HP Cell Vitaran Skin Booster is a topical cosmetic product you use at home, with a broad ingredient blend of CS PDRN salmon DNA plus 54 actives. They are different formats, and the Vitaran option suits people who prefer a routine without injections.




