Short answer: the best microneedling serum is one that suits your skin goal and absorbs well through the micro-channels, most commonly a PDRN, exosome or hyaluronic acid serum. Below we compare the top options and how to choose.
When it comes to microneedling, the serum you pair with your routine makes a real difference to the look of your results. With so many on the market it's hard to know which to choose, so here's a clear guide to the most popular, well-formulated options, all available at Salmon DNA Australia and shipped from Brisbane.
What is microneedling?
Microneedling is a minimally invasive cosmetic technique that uses fine needles to create tiny micro-channels in the skin's surface. At home, this is done at a gentle depth (typically 0.25-0.5mm). Applying a suitable serum afterwards helps those actives absorb and supports the appearance of smoother, more hydrated skin.
Why the right microneedling serum matters
A well-chosen serum adds hydration, comfort and targeted actives. The ideal pick supports skin comfort, boosts hydration and suits your specific goal. Here are the standouts.
1. Jeunetique EXOsomes & PDRN 3%
Formulated with exosomes (tiny vesicles that help carry actives into the skin) and PDRN (polydeoxyribonucleotide from salmon DNA).
- For the look of repair: a popular choice for the appearance of scarred or uneven skin.
- Hydration boost: helps replenish moisture for a plump, dewy finish.
- Smoothing: supports the look of firmer, smoother skin over time.
2. Hyaron HA
A DIY-routine staple: 10 syringes of 2.5ml each (2.5ml covers your whole face, neck and décolletage), a concentrated hit of hyaluronic acid that can be layered with other serums to cover the hydration side of your routine.
- Deep hydration: long-lasting moisture for supple, smooth-feeling skin after microneedling.
- Easy absorption: low molecular weight HA absorbs readily through the micro-channels.
- Soothing: helps calm the look of post-treatment redness for a comfortable experience.
3. HP Cell VITARAN Salmon DNA Serum
An advanced salmon DNA (PDRN) ampoule formula that pairs PDRN with hyaluronic acid and a broad blend of vitamins and amino acids, a lovely companion for at-home microneedling routines focused on hydration and a refreshed, even-looking complexion.
- For the look of renewal: supports the appearance of fine lines and uneven tone.
- Hydration: a soft, luminous finish.
- Routine-friendly: designed to be layered into a regular at-home routine.
4. Plant stem cell serum
Plant stem cell serums are increasingly popular in microneedling routines. Rich in antioxidants, they help support skin against environmental stressors and are known for their soothing feel, a nice option for sensitive-feeling skin prone to redness.
How to choose the right microneedling serum for your goals
- Skin type: Hyaron HA suits dehydrated skin; a PDRN ampoule like HP Cell Vitaran suits those focused on firmness and tone.
- Specific concerns: for the look of acne scarring or ageing, reach for a regenerative-feel serum like exosomes with PDRN.
- Desired finish: hydration, a smoother look, or overall radiance; each serum leans a different way.
Final thoughts
The right serum can elevate your microneedling routine. Whether you choose exosomes with PDRN, the hydration of Hyaron HA, or an HP Cell Vitaran ampoule, each offers something different. Still unsure? Browse the full microneedling serums & skin boosters collection or pair your serum with a device from our DIY beauty devices range.
Shop microneedling serums & skin boosters →
Frequently asked questions
What is the best serum to use with microneedling?
The most popular choices are PDRN, exosome and hyaluronic acid serums, because they absorb well through the micro-channels and support hydration and a smoother-looking finish. Match the serum to your goal: hydration, the look of scarring, or overall radiance.
Can I use a PDRN serum for microneedling at home?
Yes. PDRN salmon DNA serums are a popular topical companion for gentle at-home microneedling (0.25-0.5mm). Always patch test first.
Do I need hyaluronic acid as well as PDRN?
Many people layer them. HA covers deep hydration while a PDRN or exosome serum targets the look of firmness and tone. They complement each other well.
Disclaimer: These are cosmetic skincare products. Always patch test before use. Not suitable for those with fish allergies. For at-home microneedling use a gentle depth and follow device instructions. If you have a specific skin condition, consult a skincare professional.
