216 reviews
Updated April 2026 · about a 7 minute read
The gentle, injection free way to enjoy salmon DNA at home, one step at a time.
The short answer
Rejuran is a clinic injectable built around salmon DNA (PDRN and PN), a procedure for qualified clinicians and a therapeutic good we do not sell. The safe way to enjoy salmon DNA at home is a cosmetic serum you apply, paired with a gentle treatment. Here is how it all fits together. Browse salmon DNA serums.
If you have been reading about Rejuran and wondering whether it is something you can do yourself, this guide is for you. There is a lot of overlap in the words, salmon DNA, PDRN, skin boosters, so let us untangle what belongs in a clinic and what belongs in your bathroom, and point you to the salmon DNA skin boosters you can actually use at home.
Editor's note, June 2026: there have been more advanced formulations on the market since Rejuran became available in Australia back in 2024. The best one currently, which holds the highest percentage of salmon DNA and also contains exosomes, is Jeunetique EXOsomes PDRN 3%.
What is salmon DNA (PDRN)?
Salmon DNA skincare is built around PDRN (polydeoxyribonucleotide) and PN (polynucleotide), DNA fragments purified from salmon. As a gentle, biocompatible cosmetic ingredient, it is valued for supporting the look of hydrated, calm, even skin over time.
What people love about it (cosmetically)
- Hydration: PDRN helps draw in moisture for a plump, dewy look.
- The look of smoothness: supports the appearance of softened fine lines over time.
- The look of firmness: supports a more even, resilient looking complexion.
- Comfort: a gentle, soothing feel suited to sensitive skin.
- Low fuss: easy to use consistently with minimal downtime.
Important: Rejuran (injectable) is a clinic only procedure
You will often hear the word Rejuran in the context of an injectable treatment. Rejuran is a therapeutic good, and injecting any product beneath the skin is a clinical procedure that must be performed by a qualified, licensed clinician in a regulated setting. It carries real risks (infection, scarring, vascular and nerve injury) and is not something to do yourself at home. We do not sell injectables, and nothing here is intended to be injected. We mention Rejuran for context only. If a clinical treatment interests you, book a consultation with a licensed professional.
Rejuran belongs in a clinic. Salmon DNA that you apply at home belongs to you.
The safe at home alternative: salmon DNA you apply, plus a gentle treatment
The good news is you can enjoy salmon DNA cosmetically at home, no injecting, with a salmon DNA serum you apply, optionally paired with a gentle treatment (0.25 to 0.5mm) to help it settle in.
What you will want
- A salmon DNA (PDRN) serum you apply to the surface of the skin
- A clean at home skin tool (a roller, stamp or pen) with single use heads
- A gentle cleanser, a soothing mask, a barrier moisturiser and SPF
- Optionally, an LED red light for a comforting finish
The gentle method
1. Cleanse and pat dry.
2. Numb only if sensitive, then wipe off excess.
3. Gently work over the skin at a shallow depth (0.25 to 0.5mm) with clean, single use heads. Keep plenty of serum on the skin so the at home skin tool glides (dragging on dry skin can cause irritation), and never go deep enough to draw blood.
4. Apply your salmon DNA serum throughout, and coat the skin at the end. The tiny channels stay receptive for a few minutes.
5. Mask and LED (optional), then a barrier moisturiser.
Aftercare
A little redness (like mild sunburn) is normal and usually settles within a day. Avoid heavy makeup, sun, saunas, steam and exercise for at least 24 hours. For the full routine, see our aftercare guide.
How often and what to expect
A common rhythm is a gentle session every few weeks, with a daily salmon DNA serum in between. Results are cumulative, most people notice the look of more hydrated, even skin over several weeks. An at home routine you apply yourself is also a budget friendly way to enjoy salmon DNA compared with clinic visits, and, unlike a clinic injectable, it is a cosmetic you apply yourself.
Final thoughts
Salmon DNA is a lovely, gentle way to support the look of healthy, radiant skin. Injectable Rejuran is a clinic procedure for qualified clinicians, and a therapeutic good we do not sell, but for a safe, at home cosmetic routine, a salmon DNA serum you apply with a gentle treatment is a beautiful option you can do yourself. Always prioritise skin health, and consult a professional if you are unsure.
CureNex Salmon DNA Rejuvenating Face Cream 120ml
A rich salmon DNA moisturiser to seal in comfort and hydration, lovely on its own or after your at home skin tool.
$79 AUDAfterpay available · free shipping over $150Shop the face cream →
Frequently asked questions
Can I do Rejuran at home?
No, injectable Rejuran is a clinical procedure that must be performed by a qualified clinician, and it is a therapeutic good we do not sell. For home use, a salmon DNA (PDRN) serum you apply with a gentle treatment is the safe cosmetic alternative.
Is salmon DNA skincare safe to use at home?
Yes, salmon DNA serums are made for at home use on the surface of the skin, on their own or with a gentle treatment (0.25 to 0.5mm). No injecting.
How often should I use it?
A gentle treatment every few weeks, with a daily salmon DNA serum in between, works well for most people.
Disclaimer: these are cosmetics, not therapeutic goods, and are not intended to diagnose, treat, cure or prevent any disease or condition, and are not for injection. Injectable treatments like Rejuran are clinical procedures for qualified clinicians only and are referenced here for context; we do not sell them. An at home treatment should be gentle (0.25 to 0.5mm). Always patch test; not suitable for those with fish allergies.
